Melatonin’s Magic on Your Hormones – With Dr. John Lieurance

Dr. Mindy
I want to give my followers a little bit of a context into how I met you and got familiar with your products. And so resetera is listening to this. I met john at a conference and he had some really unique products. And of course, I’m always want to try stuff on myself first. So I took two of them home with me and one of them is this product called Sandman. And it’s a melatonin suppository. And so when I first tried it, I was a little dubious, but sleep for menopausal women especially is a big issue. So I’m like, Okay, well, let me give it a go and see what happens. Holy cow, I was like, not only knocked out and slept incredible. Not only did I wake up refreshed, but my whoop score was insane. I was shocked. I was getting up every morning. With 100, almost 100% recovery, everything was in the green. It didn’t matter how long I slept. Something was happening to my body at night when I used the Sandman. So you have to start off, we have to start off this conversation, john by you explaining to me and I reproduced it over and over again. I tried doing it without using the Sandman. And sure enough, my recovery went down. So talk to me about melatonin gluta thigh on this Sandman a product and why it works so well for me.

Dr. John Lieurance
Wow. So thank you for having me as a guest, I’m so grateful to be on and to be speaking to your listeners. So I just released a book on melatonin. It’s called melatonin miracle molecule. We have literally like, I think 17 chapters. And I mean, we get into cancer, we get into the mitochondria, we get into infection, we get into the microbiome and the gut, we get into liver, we get into mental emotional, we get into autism. I mean, it’s just

Dr. Mindy
all of that can be helped with, with melatonin.

Dr. John Lieurance
it’s mind blowing. it’s mind blowing, because it’s every there’s so many things that are hardwired to our circadian rhythm. And what’s happening right now. So well, let’s first start by so the early research with melatonin, what they did is they took rodent models, and they gave them melatonin, and then they obviously had a placebo group and they didn’t notice any difference. And so the researchers were like, yeah, you know, we don’t really see any difference in melatonin. And so not too long after they changed the study around because, you know, basically, in normal environments, rodents are basically living like, at the Ritz Carlton, there’s zero stress. I mean, they got nothing to worry about. They’re fed Great. So what they did is they added stress to these rodents. And the way they did that is they created these little tubes, and they poked holes in the tubes. And then they stuffed the mice in there for like several hours a day, which as you can imagine, is could be very stressful. And this is the way they mimic stress. And so then melatonin benefit really started to shine, they’re seeing the rodents didn’t succumb to a lot of the different diseases associated with stress. So you want to think about melatonin as a as a stress resilient substance. And this is where you start getting into signaling factors between your sleep and you’re and you’re in your wake cycle, right? So there’s things that happen when we’re awake. And there’s things that happen when we sleep. And the problem is, in today’s world, there’s a lot of light pollution, eat but by the way, EMF, like those, those rays actually go and hit your pineal and your pineal thinks it’s daytime

Dr. Mindy
EMF being not necessarily just blue light. This is like what’s coming off my phone off my router.

Dr. John Lieurance
Wow. So a good reason to turn your router off at night. Because if you could imagine you’re sleeping. And these these, you know, these microwaves penetrate very well, right? So they’re hitting that pineal and your pineal isn’t really giving you the strong signal that you need to be to be asleep. And so it also suppresses melatonin. And you know, there’s a lot of research that shows that, that these, these microwaves, these emfs are cancer producing. So if you look at how well melatonin has been shown in research to suppress cancer, you start to put in and connect the dots a little bit. You start realizing how massively important Melatonin is and a normal graph that drops off so dramatically, especially after the age of 40. So even in a normal state situation, we just don’t have melatonin as we get older. So the need to supplement it and much higher than I think what a lot of people have traditionally recommended. Oh,

Dr. Mindy
yeah.

Dr. John Lieurance
I mean, what we got you on 200 milligrams,

Dr. Mindy
right. That’s what I noticed, because I was and and I don’t know if it was the difference between a tablet versus depository, but wow. I mean, it really was like, I felt like you had given me a missing ingredient that my body needed and never had received before. Because the whoop, if I hadn’t seen it on my whoop, I would not have believed it, I would have thought it was in my head.

Dr. John Lieurance
Or, you know, I’m not familiar with the whoop, I use the aura. Is it showing you heart rate variability?

Dr. Mindy
Yeah, so heart rate variability went up. But what I what I look at a lot is recovery. Because if and it gives you like a green, yellow, red, and I struggle to get into the green a lot. And what that means is, hey, what your sleep was so good, you’re ready for like stress that day?

Dr. John Lieurance
Your stress resilience. Yes. Right. So that’s what? And so this really has to do with the autonomics. Right? The sympathetic, parasympathetic, right? And so, you know, do you think people are too parasympathetic dominant?

Dr. Mindy
I don’t I haven’t met anybody who’s to parasympathetic yet. No, I don’t. My husband might be, but

Dr. John Lieurance
that might be why I live with them. Well, for listeners out there, you know, so you have two sides of your autonomic these are, this is a part of your nervous system that is operating behind the scenes. And so there’s the resting and digesting, which we call parasympathetic. And then there’s this fight, fight, flight, fight, flight, or hide, which is the sympathetics. This is where we have a part of our nervous system that’s literally there for us to escape. Imagine that you had like a tiger chasing you or something. And so there’s some changes that happen physically to you, that really shouldn’t be in a chronic situation. But we are locked into this stress response. And even the I think, even the healthiest, calmest person, just because of today’s world, there’s just so many stressors, yeah, that people are going to be a little bit more dominant on the sympathetics. And so what that does, is it really challenges our recovery, because recovery is going to be in the parasympathetic. So if you’re constantly in this, in this fear, stress state, it really ages you, you know, and if anyone’s listening to this, and they’ve got like a disease that they’re dealing with, if it’s mold, or lime, or autoimmune, or hashimotos. I mean, every single cancer, whatever, you’re going to survive and thrive if you can get yourself more into the parasympathetic healing stage. Yeah. The biggest promoter of that is Guess what?

Dr. Mindy
melatonin? Absolutely,

Dr. John Lieurance
yeah, that’s in the research, it shows the tone to the parasympathetic is incredible. This is when we sleep, our body goes into this massive parasympathetic state. And so this is where we kind of catch up and we heal our body. So heart rate variability is something that we look at. And I, you know, I took a deep dive into heart rate variability, I didn’t really understand it for years. And then I really took a look at it and how it relates to melatonin. And what I found is that the heart is controlled by both the sympathetic and the parasympathetic nervous system. And so they both are jumping in, they’re giving the heart signals. And so the variability comes because the sympathetic and the parasympathetic are coming in and controlling it in different stages. And so it varies because they’re both working on the heart. When only one of them is predominant, it’s going to be more consistent because you only have one side of the autonomics that are that’s running the show. And again, is it ever a parasympathetic problem? Never.

Dr. Mindy
So but so when I’m taking melatonin, I’m strengthening parasympathetic, which allows parasympathetic to come in and counterbalance my sympathetic nervous system better. Is that exactly the way I would look at this? Yeah,

Dr. John Lieurance
yeah. Well, you know, I think about when I train at the gym, if I only work my bicep muscle, my tricep muscle, there’s something called reciprocal inhibition. The nerves are going to actually tell this muscle to stop working, right so that it’s all about balance. And so if you have a strong sympathetic, you’re going to have a weak Paris. Something so you, you have to take your parasympathetics to the gym. And so my, you know, breath work, I love getting patients on breathwork because that’s a window into, because you have volitional control to your breathing, and you have non volitional. So it’s one of those things where you’ve got the two windows kind of feeding into that. So breathwork actually is very good at strengthening the autonomics is particularly the parasympathetic. Yeah. And then there’s sleep and melatonin. If you look at the chart with heart rate variability as you get old, like it’s the same chart with melatonin. Oh, that’s you just put those next to each other, and they look like almost the exact same chart. So is it possible that people are looking at heart rate variability as this huge indicator for disease when it’s a reflection of their melatonin?

Dr. Mindy
so fascinating, because again, when I got Sandman at the seminar, and then I saw I mean, I’ve been tracking my heart rate variability and sleep for over a year. Now when I saw that dramatic shift, and I’ve tried, you know, is it water? Is it electrolytes? Is it magnesium? Like, I’ve tried everything? And when I saw that, I thought, okay, something’s in this. I don’t know what it is. And then of course, I was like, Oh, well, maybe it’s the first night I did it, then maybe it’s the second night, I literally finished the first pack of it, which I think there’s like 10 of them in a pack or so I went 10 days, and I was completely in the green recovery all 10 days, I’d never seen that not even on a fast. And then I was like, Well, let me go off of it. Went off of it. And it went back down to yellow and red. My recovery wasn’t a good. So I’m like, Okay, let me try it again. Let me get get more Sandman. So I got it again, back up to green. Like it’s crazy. So there’s definitely something in there. That I mean, I what you’re saying, I feel like I saw an action in my body. My question is, why would the body stop making melatonin after 40? What is the primitive reason for that?

Dr. John Lieurance
Boy, that’s, that’s a tough question. You know, um, I think just having birthdays in general, I think we’re basically genetically. You know, we succumb to that aging process. And I think all of our glands and our ability to produce melatonin in general. You know, I think it’s a lot worse now than it probably was, you know, in early days, if we’re not getting enough sun. So sunlight on the eyes is incredibly important for you to produce your own melatonin. Yeah. And so one of the things I see people do is they, you know, they wake up in the morning, right, and they, as soon as they walk out their front door, they put the sunglasses on, they keep them on, on their drive to work. Right, they get into work, they’re under fluorescent lights. So it’s like I did sunglasses, and yeah, so you don’t need them. If you don’t, you know, if I’m on the beach, and there’s a lot of reflection or if it’s like in the middle of the day, occasionally I wear sunglasses, but I think people are way too, hyper paranoid about like, different problems with their eyes based on sunlight when I don’t think that it’s warranted unless there are certain scenarios where there’s going to be a lot of strong sunlight, but we’re talking about in the morning, right? I mean, you want to get that sunlight in the morning to signal the body, hey, I’m awake. Let’s start making melatonin. And then at night, you know, in the evening hours, it’s also a good time to let sunlight into your eyes. And also one of the things that I did and this is in my book as well even took pictures of my house, but I got red light rope light, which I put into like my stairway and, and then I got lamps that I put around the house with red lights, so cool. And then I bought these like remote control, like light sockets, right. So you have this little control panel and you can control the light. So literally, by the time I get to my bed, I have one of those control panels velcroed next to my my nightstand and I just shut everything off. And if I wake up in the middle of the night to go the bathroom, it’s red light. It’s not that you don’t want that white light to which has a lot of blue and green in it to signal your body. Oh, it’s morning and wake up, especially at night when you’re and then the other. The other thing that I think’s important is to wear blue blocking sunglasses when you watch TV, or look at night. At night.

Dr. Mindy
Yeah. Only at night though, right? Not during the day.

Dr. John Lieurance
No, no, because you want the blue, the blue and the green light is a signal to say it’s daytime And to produce melatonin I’m sorry, yes to produce melatonin, right? nighttime is to release melatonin.

Dr. Mindy
Okay, so talk about the difference of this because we do this, we talk about this a lot in my reset Academy that just because you make a hormone doesn’t mean you’re use it. So are you saying we, we produce melatonin in the morning in response to red light, but we don’t officially release it and use it until it’s nighttime.

Dr. John Lieurance
Right? So the signal is to store it. And then the darkness is to release it.

Dr. Mindy
And where does it get stored?

Dr. John Lieurance
Well, I’m in the pineal, but you know, again, we actually dose so if we have cancer patients, or if we have severe neurological cases, or even autoimmune, or we’re working a lot with mold, and Lyme cases with these high doses of melatonin, and we’ll even dose people during the day and only about 20% of the population will get groggy. Most people can tolerate even these really high doses of melatonin during the day as long as there’s light.

Dr. Mindy
Interesting. So it’s at so you produce it in the morning in response to light. And then when the red light of like a sunset happens again, that is your body’s knows Hey, now we got a lead release it so this person can go to sleep, right? Yeah, it’s worse. We’re so intelligently designed. It just blows my mind, the more I study, I’m like everything we are desiring for our body to do it’s already doing we’re just messing it up by living in this modern world. Totally. What part of the of the body? So you talked about the pineal gland. I’ve also heard that Melatonin is produced in the gut, is that right?

Dr. John Lieurance
So there’s the Melatonin is actually produced in every single cell in your body. And each mitochondria uses melatonin to buffer stress. So we’re talking about all the way down to the most important part of your cells where you make energy, where energy happens. It’s called the mitochondria. Right? So this is where oxygen and glucose is converted into something called ATP that fuels everything that happens in your body. And so what happens is when we have stresses, we have cytokines, so there’s a variety of different cytokines, which are inflammatory compounds, and those inflammatory compounds have need to be buffered. And and so what happens is they, they, they they have an effect on our cell, such that cytokines convert our energy production from a very efficient Krebs cycle, which, so normally, when we make energy efficiently, we’re making about 38 ATPs, from one from one glucose molecule. Okay. When we have cytokine stress, there’s a shift in the way we make energy. They call it the Warburg effect. Have you ever heard of Otto Warburg?

Dr. Mindy
I have? Yes. Right. So yeah, the guy who said cancer is a mitochondrial, it’s a cellular issue, not a gene issue.

Dr. John Lieurance
He won the Nobel Prize in the 40s, for discovering that oxygen and cancer can’t coexist. And Hitler did not let him pick up the Nobel Prize, unfortunately. Right. I mean, it’s back then. But, but so he had some early, profound discovery discoveries on cancer, which, honestly, even today, they’re not embraced, because Big Pharma patentability, blah, blah, blah. I mean, oxygen is not something you can fatten, right? Right. So the Warburg effect basically says that a cell under so much stress turns into fermentation, which is a primitive form of energy production. And so what people don’t realize is that whole process basically yields about a 10th of the amount of energy that you would otherwise get. So if that if we’re talking about immune cells that are requiring this energy to fight infections, and then all of a sudden they have a 10th of Mount of the energy, you can just imagine how an infection could overwhelm them, whether it’s epstein barr, CMV, hhv, six, Lyme disease, you look at every infection, right? So that’s why Lyme is so destructive to your mitochondria because the cytokines you know, the chronic inflammatory response syndrome is what I like to term better about. The whole family have biotoxin illness, right? Because it’s more of a situation where people are toxic from the bio toxins, and that’s the cytokines are having a negative effect to their mind. Andrea, and then they just can’t, they can’t, their cells can’t do what they need to do. So these are all good.

Dr. Mindy
So does the mitochondria. I know that the mitochondria makes Bluetooth ion does it also the part of the cell that produces mela tonin?

Dr. John Lieurance
Well, it’s in the might, actually inside the mitochondria. When pirate eight comes down, there’s like a whole separate cycle where Melatonin is produced primarily when there’s too much oxidation. So there’s a mechanism in there that detects when there’s a higher level of oxidation. And melatonin then comes in and quench is that when that system is overwhelmed, and the melatonin can’t do enough, because it’s too much stress, then we shift to this aerobic glycolysis, which is, which is not a the the fermentation. And so what happens is if you give supplemental melatonin, they’ve actually discovered that not only do you calm down all of this inflammation, but it actually gets the mitochondria to start making melatonin again. So it’s really amazing.

Dr. Mindy
Yeah, well, and I was wondering why you put glue to tie on with melatonin in Sandman. And what I’m hearing from you now is that it’s really about repairing mitochondria, which is why not only am I getting a better recovery, but you can also say hey, this is helpful for autoimmune cases and autism. And so the reason so many people have such low melatonin really comes from this place of a dysfunctional mitochondria. Am I connecting those dots? Right?

Dr. John Lieurance
I you know, I think that would be a fair assumption. And you know the answer. So why did we put Bluetooth on in there? First of all, I think he would have found it very helpful for a lot of different you know, it’s good for viral immunity. It’s good for detoxification. And it’s also one of the sleep promoting substances. So for people to fall asleep, right, so there’s two main sleep promoting substances, it’s euro Dean, and the reduced form of Bluetooth ion. So it’s actually you know, the the the Sandman has really been formulated to really help with sleep, there’s actually CBD in there. There’s something called Magnolia bark extract, which is really good for sleep. And there’s also linalyl, which is the active terpene from lavender. Hmm. So, um, so it’s really been silenced out to really help. And you know, there’s no prescription medicines that will give you true sleep.

Dr. Mindy
Right? They just explain that a little bit. Because I think, again, you’re talking to an audience that insomnia is a big deal when you’re dealing with women over 40 which is why I think it’s so interesting that melatonin production goes down, while a woman’s hormonal cycle is plummeting. At the same time, this explains a lot. But what if I take an Ambien? What if I take something that just helps me knocks me out? That’s not actually a reparative? sleep?

Dr. John Lieurance
Good question. So this is the way I would look at an Imagine if you had someone two people, one person fell hit their head, and they’re laying on the ground passed out, right? And then you have someone else that has gone into a nice, beautiful sleep, and you put them next to each other in a bed, they’re gonna look pretty much the same, right? Yeah, but when they wake up, they’re gonna feel quite different. Well, sad. So these, these prescription drugs knock you out. But what you have to understand is that sleep is like this Symphony, you’re going in and out of REM and deep sleep, and there’s all these pulsing things. And it’s it’s it’s really this this beautiful song that’s being played throughout the evening. And you’re basically just suppressing all that.

Dr. Mindy
Right. Right. Yeah. So do you think that the reason I mean, I’m now connecting us several dots, I’m thinking, Okay, the world is got a lot of mitochondrial dysfunction. And we that’s leading to insomnia that’s leading to immune compromised people, millions of people across the country as we saw our the world over the last year, it’s leading to all these diagnoses and yet what we’re trying to do is support his treat these diagnoses with medications that are destroying the mitochondria, even more suppressing melatonin gluta find even more contributing to more possibilities for infection and toxicity. It sounds like a vicious cycle to me.

Dr. John Lieurance
Exactly. Right. It’s it’s just, we weren’t built to be resilient to as much stress as we’re being exposed to. And you know what I you know, what I loved about because you I don’t think we really mentioned this in the beginning too much. But you and I shared a stage recently. Yeah,

Dr. Mindy
that’s right. I could have I could have profiled us a little that way we did share a stage together.

Dr. John Lieurance
So you know, our beautiful, amazing friend and colleague, Dr. Dan pompe, who we love so much and has contributed so much to a lot of the different wisdoms that we share, put on a presentation in Salt Lake City. And I would say the overall theme was hormesis and stress, and how that stress is not so bad. And if it’s in the right amount, I mean, think about that. So we have a familiar zone, right? We’ve got this familiar zone, and people want to stay in that familiar zone, when you go just outside of that familiar zone, you go into this realm, as long as you don’t venture too far out, you go into this realm that actually stimulates signaling pathways in your body to make you stronger. Mm hmm. Right. And what I see is melatonin expanding that, that that that that rim around the familiar zone, so that you can venture out and you can give your body more exercise stress, you can give yourself more mental emotional stress, you can do more chemical and toxic stress, infection, stress, all of those things your body can handle more with and with proper melatonin,

Dr. Mindy
so you can move into more hormetic stressors. And I end just to point out for listeners, that means a little a little bit of stress. This isn’t like chronic stress, but a little bit of stress, like an ice bath or a fast which I want to get into here in a moment. So Melatonin is going to assist you in adapting to that stressor. Is that what you’re saying? Yeah, yeah,

Dr. John Lieurance
it’s gonna last, it’s gonna also allow you to take on more of that cold. Mm hmm. So it’s gonna increase that ceiling.

Dr. Mindy
So could I use melatonin to prepare myself for longer fast?

Dr. John Lieurance
You could Yeah, we use melatonin. Very, we really promote it for the post fast component. But you could take it all the way through,

Dr. Mindy
all the way through,

Dr. John Lieurance
I have a lot of patients that I’ll put on melatonin, you know, I think one of the most amazing things that any human being can do, especially if they’re over 40, is do a full three months of daily melatonin and just watch what happens,

Dr. Mindy
melatonin may be the missing piece for me on a consistent basis. So I’m as excited about this as perhaps people that are listening, because I like this idea that we’re supposed to have natural nutrients in our body to allow the human body to function normally. But the modern world we’re living in is depleting that. And I don’t think we have enough conversation about this is what I love about fasting, I’ve now come to this point where I’m like, the majority of the world is poisoning themselves every single day when they eat. So if we can’t change the food industry, if we can’t change people’s food habits, why don’t we get them fasting, so they can at least click in and repair a little bit. And now what I’m thinking with melatonin and even Bluetooth ion is like, Okay, if we can’t change the blue light, we can make some rec, some changes to it if we can’t change the EMF as quickly as we want, which I know you’ve done a lot of work in your office in your home with why don’t we start supplementing with these nutrients to be able to combat this modern world we’re living in?

Dr. John Lieurance
Yeah, you know, and I think this is a good segue to maybe roll into fasting.

Dr. Mindy
Right? Yeah, I was gonna ask you like when you you know, when I talked to Ben about interviewing you? He’s like, Oh, you could go down any path with him. Ben Azadi and he’s like, he’s the ultimate bio hacker. And I think what I want to say to our listeners is that the cool thing about bio hacking is it’s really you’re tapping into the mitochondria at the base of all biohacking. Right. Yes. Like mitochondrial health, which really is what fasting does as well as repair that mitochondria. I cannot wait to have you join us in the next fat burner reset. We’re seeing something really unique happened across all of our platforms. And that is that people for the first time are losing weight like never before. And let me tell you why. The calorie in calorie out mentality of fat burning of weight loss, it’s broken. If that worked, we would have solved the obesity problem years ago. And so many of you have hopped on diets only to have it have a temporary result or to have it fail and you stop believing in Your own power to lose weight. So in this reset, I’m going to show you a whole nother way to lose weight. And it’s called metabolic flexibility. And what we’re going to do is I’m going to take you through a 15 day experience, where I show you how to move from being a sugar burner to a fat burner. How do you move in and out of these two states. So there is a magical way of doing this. When you teach your body how to be a fat burner, you will drop weight like nobody’s business. And you will see that you’ll drop weight in a very unique way. But that’s not the whole part of the story. I also want to show you how to be an incredible sugar burger. So that that might sound kind of weird. But there is a way to eat so that you lose weight, there’s a way to fast so you lose weight, there’s a way to exercise so that you lose weight. And there’s a way to move in and out of these two states that will finally get you the weight loss result that you’re looking for. So join me in the July reset, I’m going to walk you through a 15 day experience, we’ve got an incredible community of people in there to support you, I’ve got my reset guides. And the best is we’re going to teach you how to lose weight for good. And you’re going to not only learn it for the fat burger reset, but then you have that tool, you can train your body to be a fat burner for the rest of your life. So join me is super excited to show you what you can accomplish with your fat burning capabilities. Jump into a toffee g talk about fasting, I love your ideas about what to do before and after a fast so that we can really power these mitochondria up.

Dr. John Lieurance
So um, so basically, what I was looking at is being able to provide the stronger signaling for for fasting. And so fasting is a stressor. So it’s like a hormetic stress. So things that we can do that can like expand that out of the familiar zone and allow us to dip into that stress zone and have a more powerful healing reaction to that. So one of the things that I thought of was charging the mitochondria before the fast and we use an ad. You know, the benefit to na D was very obvious very early on. And we talked about sleep and poor sleep is one of the biggest drainers of an ad. And what any he is it’s a rate limiting substance that the mitochondria needs to make energy. And we become depleted with this of this is an ad from stress. And the two biggest ones are toxins and poor sleep. And among the toxins are drugs and alcohol. But this is the other thing nobody’s talking about with with na D is senescence cells. So let’s first of all, let’s talk about what is a senescent cell? Why do you want to know about it? What can it the harm it can do to your body, etc. So in your body, you have cells that have not been cleared out and recycled. And especially as we get older for in disease states, these accumulate and these are like old cars that really need to be cleared off the road. They’re spewing pollution, they’re hogging too much gas, and they’re just not doing any work. Right? So these are called senescent cells, and they’re incredibly inflammatory. And we all have to deal with these. Okay, so things that we do to clear up senescence cells, which is primarily like fasting, because that causes autophagy, which clears out senescence cells in your body. And so fasting is a signaling but there’s also plant extracts that are considered senolytics. Okay. And the most powerful that of these synthetics is Pfizer, Tim, have you heard of Pfizer?

Dr. Mindy
I haven’t.

Dr. John Lieurance
Okay, so it’s from strawberries, but you’d have to eat a truckload of strawberries to get the amount but interesting, but sterile still being is from blueberries. It’s also a very powerful synthetic. Okay, curcumin is also a powerful synthetic, not as much. So a lot of these really colorful plant extracts. That’s how they work is there and they can be very good to take while you’re fasting. Because they basically give you an extra push for a toffee G and to clear out senescence cells. But the reason I’m bringing this up with the conversation about na D is that na D support senescent cells just as much as it supports your other cells. Okay, so you don’t want to take na D every day.

Dr. Mindy
I was just gonna say but you don’t want that. Now Yeah, especially when you’re fasting. Right? Yeah. Because fasting you’re trying to get at the senescence cells, right. Got it.

Dr. John Lieurance
So Paul, we what we recommend people do is they pulse the NA D, so you don’t want to take any D every day, you just take it, you know, a few times a week. So are our Mito fast we have people take, depending on what type of fast they want to do, you know, if they want to do a two day or three day or a longer, it’s three phases. So the first phase, we load them with an ad. The second phase is the actual fast. Okay, so we have them fast, but we take that we have them do the phase two, which is the lucid tall. So lucid tall is a product that comes in a suppository, and it also comes into life zomo for those that would prefer the oral, and that’s done while you’re fasting.

Dr. Mindy
And what is lusitano do it helps to get rid of the senescent cells,

Dr. John Lieurance
it’s got the cynnal, it’s got the Pfizer, General spill still being it’s got green tea extract, it’s got gingko it’s got lutein, I mean, it’s loaded right with all those.

Dr. Mindy
So it’s helping, it’s helping with the process of autophagy. It’s helping to get rid of these aging cells. So everything that we talked about with fasting, what I hear is that middle phase while you’re fasting, you’ve this lusitanian will help to facilitate that and make your fasting efforts more effective.

Dr. John Lieurance
Exactly. Right. So you know, you’ll get more effect from a shorter fast. So for people that maybe don’t want to do a five day fast, you’re likely to be able to get into max a toffee g much quicker. Wow. And stronger, deeper.

Dr. Mindy
Wow, I have a lot of resellers are going to want who are going to want to get that result. I mean, we’ve get asked this a lot like Do I really have to go three days? Do I have to go five days? And I always say well, it’s what you’re trying to do with your fast. So what I’m hearing you say is using a product like minus n, then you’re going to be able to or Mito, fast, sorry, that you’re going to be able to use that to facilitate the autophagy experience for the cell.

Dr. John Lieurance
Right. So the other thing that’s important for people to understand is that just as important as the fast is the post fast eating,

Dr. Mindy
yes thing. So

Dr. John Lieurance
I think so many people miss out on that part, because the body’s just primed to do a few things. One is you’ve you’ve broken down, you know, a lot of different cells and cellular components. Now it’s time to rebuild them. Right. And the biggest trigger to that rebuilding is a gene called m tour. So you want to activate m tour, and the biggest activator of it is amino acids and proteins. Right? So we recommend people use like, the like, perfect aminos. Do you use that?

Dr. Mindy
Yep, yep. Yeah.

Dr. John Lieurance
So we like that. And then I designed a product called stem tour. Okay, and stem tour has the the primary amino acid that really activates them tour is L leucine. So it’s primarily l leucine. But deer antler velvet is a good power activator and rhodiola. So we have all that wrapped up into STEM tour. So you take that phase three, we recommend that you increase your dietary proteins, and also take something like essential amino acids.

Dr. Mindy
So basically, what you’ve done is you say, Okay, this is what the body is doing. When you’re fasting, this is how you can power yourself up. Before you go into a fast, here’s how you accelerate your fasting results. And then here’s how you make sure that the results of those fat of that fast are enhanced.

Dr. John Lieurance
Right, you know, I left something out. So after the fast, we have to think about a few other things. Now this is where things might get a little complicated, right? So I want people to understand that they can leave it at that. Right. Okay, that is the basic fast.

Dr. Mindy
Well, just one pause for a second. Most of our listeners who are fasting aren’t even doing that. So I just I’m hoping that our expert fasters are going to go hey, this was next level. Now what I think you’re going to tell me is even now there’s

Dr. John Lieurance
a there’s a there’s another level. Okay, so the now that the other level is, you know, the microbiome, the microbiome is stressed when you deprive it of nutrients. So it’s going to be survival, the fitness fittest, you’re going to get rid of a lot of the bad guys. The healthier bacteria are going to be left. But there’s something called microbiome swarming. You and I were talking about a little bit of Oh, I know. That’s great.

Dr. Mindy
Yeah, I’m like you all you have to do is say micro micro biomes for me, and I’m like, tell me, tell me How do I swore my microbiome I assume with good things?

Dr. John Lieurance
Well, your gut produces 400 times more melatonin than your brain. Wow. And so your microbiome is on the same schedule as you are, there’s a sleep wake cycle. And so they respond to the circadian rhythm at the same time, in the same way that you do. So while you’re sleeping, your microbiome goes into a swarming effect, and it’s basically rate limiting based on melatonin.

Dr. Mindy
That’s so cool. That sounds like they have a party when we’re sleeping.

Dr. John Lieurance
They do. Oh, yeah. They do. And, and so well, they’re going through the repair phase, and they’re in the rebuilding phase. Okay, so what we like to do in the phase three, as an added upgrade is will hat will will like to have people do the Sandman. Okay, we’re a high dose melatonin, right?

Dr. Mindy
So go ahead.

Dr. John Lieurance
So there’s a couple other so there’s, there’s basically three optional upgrades on the phase three. So imagine, after you’ve done your fast, you’re also gonna release a bunch of stem cells, right? So there’s all these stem cells and one of the things because we do stem cells here, you know, we had a case, just yesterday, we will pull bone marrow and we’re doing this guy’s rotator cuff and his hip and his spine. And, you know, it’s it’s fabulous technology, right? It’s like this amazing things that we can do now to help people and without surgery, right, but we know that if I inject stem cells from somebody’s bone marrow into their knee, the difference between someone that might get great results and people that might get mediocre results are the amount of stem cells that will go senescent. So now people know what senescent cells are, right? So this is the big conversation that all of the scientists that do stem cells have is they want to limit senescent senescence with the stem cells. So when they put stem cells, whether into intravenously or into a joint or epidural or wherever you’re putting the stem cells, there’s going to be a certain population that are going to survive, proliferate and do what you want to do to heal the body. So we want to limit the senescence of the stem cells. And what I found is I did some hard research, and I found that co q 10. And this very rare substance that they get from Brown algae called fucoidan are extremely powerful survival substances for stem cells and they limit senescence, stem cell senescence, so this is an a product called stem zehn.

Dr. Mindy
Cool, okay.

Dr. John Lieurance
And there’s other uses for it. But it’s, we also will have people if they do any type of Regenerative Medicine, with PRP or prolotherapy, or if they’re doing anything where they’re trying to repair something, they this, this stems and can be a really interesting hack for them to do for a period of time.

Dr. Mindy
And would you do it post fast? Or is it like you have your three phases with the Mito fast? And then after that, those three phases. So now with the fast you’ve really kicked out these senescent cells, you’re rebooting and cleaning things up, you’re slowing aging down, and then what a week later, you could come in, with stems on

Dr. John Lieurance
know right away, right? Right. And you start refeeding, you’re, you’re you’re releasing these, these stem cells, so support them, keep them this is think about it as stem cell survival. You know, you’re giving, it’s all about the terrain. So right, if I inject stem cells into a knee, if if the inside of that knee is more vital and robust, more of those stem cells are going to work, right? If I have somebody that’s depleted, and they’ve got, you know, deficiencies, then less of those stem cells are going to be able to survive, more of them are going to go senescent. So by providing them with adequate co q, 10, and fucoidan. It’s been shown to really help with the survival.

Dr. Mindy
Do you think we have more senescent cells in our in like, let’s just use a 50 year old right now? Like do you think a 50 year old today has more senescent cells than a 50? Or 50 year old? 25 years ago? No doubt? Oh, yeah. From just modern living? Well,

Dr. John Lieurance
I mean, think about all the toxins being dumped into the, you know, I was even hearing a stat that they said that we’re gonna have zero fish in our oceans by like, 2042. Yeah,

Unknown Speaker
you know, and

Dr. John Lieurance
it’s just, we’re just dumping so many toxins into our environment. And those are finding their way up to the high at the top of the food chain, which are, which is us. Yeah, we’re the ones that are accumulating it.

Dr. Mindy
Our toxins a major contributor to senescent cells. I think so. Yeah. There’s something you know, I’ve been in healthcare for 25 years and I just walk around in sort of a A bizarre awe of what’s going on in the human body right now. And you know, 2020 definitely gave me a whole nother sense of like something’s not right with the human body, because everything that I know about how the human body is supposed to repair tells me that it can handle new viruses tells me that it’s not supposed to start aging, and, and or even let’s use menopause, it’s not meant to go into menopause at 35 years old. I mean, there’s something and that, and the only thing I can think of is that the human body is not thriving in this modern world.

Dr. John Lieurance
And that will mean let’s just look at like aluminum, for instance, right? Just look at aluminum. Aluminum, causes the immune system to be quite stifled. And in fact, it activates retroviruses. And, you know, if you look at a lot of the education that klinghardt you know, are you familiar with duck? Yeah.

Dr. Mindy
Oh, yeah. Yeah, yeah.

Dr. John Lieurance
He talks quite quite, you know, you know, he even starts to get into the contrails. Right, and that there’s all the aluminum in the environment, just from that, you know, we’re obviously we’re getting into some controversial things, whether it’s true or not. The reality is that there’s a lot of aluminum being found in our environment in our foods, we cook in aluminum cans, you know, so it that has a detrimental effect. And so we’re just talking about one toxin, right, we can talk about Mercury, we can talk about pesticides, we can talk about, you know, plastics, you know, and they all have one common theme is that they don’t allow us to thrive.

Dr. Mindy
Right, right. Yeah. And I want to bring you back on at another time to talk about the intersection of toxins and infections, because I, we’re seeing this as you are, where just people, you know, are not recovering from things like Lyme and exposure to mold, the epstein barr like, again, and we can even look at, you know, the virus from the last year. It’s like, why did people so many people fall prey and there is definitely something wrong on a cellular level that is just not being addressed? And

Dr. John Lieurance
one, one thing I would like to say, and this is gonna be probably a bit controversial, I’m gonna say this.

Dr. Mindy
Yeah. All right. We’re all we’re all about controversy. We were actually in with this podcast we’re trying to get and all my platforms people to think for themselves, we got to get out of robotic mindset. So go for it.

Dr. John Lieurance
If you have Lyme disease, and you are going to a doctor that is putting themselves out there as Lyme literate, they’re the expert or whatever, and they are using antibiotics on you. You need to find another doctor. They will not work. You will feel better temporarily, but it will come back. And it’s because they’re obliterating your microbiome. Now, I’m not saying we don’t use antibiotics in my clinic, but we may pulse an IV antibiotic maybe once a week. Right. But I know early on, I used a lot antibiotics. And it just i’d feel better just these little glimmers, but people really need to start paying attention to how important your microbiome is everything. And even one round of antibiotics can obliterate your microbiome and it takes two years to recover. Yeah, yeah. So let’s let’s really start thinking twice about our our use of antibiotics.

Dr. Mindy
Great. Yeah, absolutely. Let me finish with this. So rapid five questions I’ve got for you. I know your background. I know you’re fascinating guy. So I have a couple of things that I wanted to run past you and ask you. You’re this biohacking King. What’s the strangest bio hack you’ve ever done?

Dr. John Lieurance
Oh my gosh. Okay, so I did this just like a week ago. A friend of mine, Anthony diclemente. Yep. Have you ever heard of him? Now he’s got the biohacking secret show. Great guy. He was here at my clinic a week ago. And so he was telling me about this. This friend of his that standing on nails while she’s doing yoga, right. Okay. They’re like, they’re like these like plates, right? With all these nails on it, which is activating all the different spots in the feet. And so he’s telling me this story while we’re at the beach, and I look over and there’s these really sharp rocks. And I’m like, Anthony, let’s go up there. And let’s let’s do so we’re standing on these really sharp rocks, and we’re doing these different stretching techniques. And it was like, You felt so good. So I, I can’t wait. He’s gonna design some. These are this is a Russian technique. And so he’s gonna be bringing some of this technology, you know, to the US and so yeah, that was like kind of the newest strangest thing.

Dr. Mindy
Yoga yoga standing on nails. Yeah, that’s crazy. Okay.

Dr. John Lieurance
lava rocks on the beach. Okay,

Dr. Mindy
I will let you master that first before I’m willing to give that ago. So what’s you I know you’ve you talk I’ve seen some interviews people have done with you about your morning routine. What do you have some key things you do in the morning that sets your day up, right?

Dr. John Lieurance
Well, I tell you, I’m really into Joe dispenza meditations. No, I am doing some deep, you know, sometimes even I wake up at 4am and sometimes I’ll even meditate for like two hours. And so I do that and then I get in my way of Japanese hot and cold plunge. So I kind of do the hot and the cold. And then I get in front of my red lights. Okay, and I’ve got a bio charger that sometimes I’ll sit in front of and do a little bit more meditation. Yeah, so I have I have a pretty epic little routine.

Dr. Mindy
Oh my god. I love it. Which meditation do you like? have his the Do you get by him off his website?

Dr. John Lieurance
Somebody shared a bunch of them with me. And yeah. So there there’s it’s it’s called the the Mac center of the magnet. Right? So it’s like this amazing. Four and a half hour heart meditation.

Dr. Mindy
Crazy. Yeah, I’ll send it to you. Yeah. Yeah. So I just I’ve been doing a lot of his stuff in the morning. And I we didn’t even talk about mitosis and but I have a whole thing now where I do red light, Joe dispenza or I’ll do Soma breathing and I do my dogs and we’ll bring you on to talk about that. And about no your time at the Zen

Dr. John Lieurance
nasal spray

Dr. Mindy
Zen native, whatever. Yeah, that nasal

Dr. John Lieurance
Mito Zen calms the company. Okay. Okay. Well, the Zen nasal spray, oh my gosh, right. So people got to check that out that meditation missed

Dr. Mindy
time. Like, I know that I’m about to go into a meditation that’s maybe 40 minutes long, and it feels like five minutes, like, I’m done. And I’m like, wait, wait, that couldn’t have been I’ve double checked my clock a couple of times. So whatever is in that Zen nasal spray? I’m like, That’s crazy. But that’s for it. We’ll we’ll bring you back on and we’ll chat about that. Okay, what book changed your life that you think everybody should read?

Dr. John Lieurance
You know, I just watched a series on Gaia with Gregory Braden, have you ever heard of Graham Graham? Yep. It’s called missing links. Okay. And this guy puts some amazing perspective. And I would just really encourage people to go on and watch that if you don’t have a Gaia subscription. The other one, Joe dispenza. Has the, you know, the rewired on there, which is Yep. Both of those will, could potentially change your life

Dr. Mindy
a great. Yeah, that’s the one I’m watching with Joe right now is called the formula. He just put it out. It’s also another really good one, not on Gaia, but I’ve it was just on his website. So what is the one health habit that you’re like, I would never give this up? I’m sure you have a lot of them. But is there one health habit that you feel like move the needle the furthest on your health? And you would never give up?

Dr. John Lieurance
Well, meditation, I would say, it’s hard to just say one, right? I know, you’re like pinning me down. I think, you know, finding out what I was allergic to, like gluten and dairy. Like I just grew up on that stuff. And I was always in a brain fog. And getting off of gluten and dairy and even eggs. For me. My diet is somewhat limited. But yeah, it’s gotten me to kind of move out of my familiar zone and play around with cooking and doing other things. But yeah, I mean, I think people should really look at a rotational diet and figure out if there’s things that are causing a lot of inflammation.

Dr. Mindy
Yeah, yeah. Smart. Well said. Okay, last question. If you had one message for the world that you would want to get implanted into everybody’s brain, what would that message be?

Dr. John Lieurance
That you can absolutely change your reality by intending it, and there’s a way to do it. And Gregg Braden says it so eloquently is you want to go into the place of that you already have that and that you’re grateful for it. And how it feels to own that like Rhonda burns a really good friend of mine, right? She wrote the

Dr. Mindy
song. Yeah, the secret. Yeah,

Dr. John Lieurance
she’s been on I have a YouTube channel myself. She’s been a guest speaker. I’m actually going to go hang out with her in July. Awesome out in California. So she’s really a beautiful human being. And so she’s been preaching this for, you know, decades, right. But his prayer is, when you pray, like I want this, I want this. The universe is looking at that light You have a lack, right? And so even the ancient Native American Indians, the way that they would go about it is they would just like if they wanted rain, they would be like, how does it feel for the rain to hit my face? How does it feel for the mud to be between my toes? And so they’re not like sitting there thinking, I want it to rain there thinking, I have the rains. Thank you so much. This is what it feels like. And so this is how we put that that information out into the field, the quantum field, right? It’s my start getting really Whoo,

Dr. Mindy
oh, no, no, you’re I’m, I’m soaking up everything you’re saying. I’m right there with you, john.

Dr. John Lieurance
Yeah. So that would be my son is lean into that, because there are some things that you can do with consciousness to hack your reality, your health, your vitality, your relationships, your financial situations, it’s real.

Dr. Mindy
Hey, resellers, I just want to start off by saying, thank you so much for all your wonderful reviews. And those of you that have left me comments on iTunes, I just greatly appreciate your thoughtfulness and how much you guys are enjoying these episodes. And it seems like you’re enjoying them as much as I am enjoying doing them. One of the things that I’ve learned in just interacting with so many people is that we’ve really lost the art of deep conversations. And for me, the reseller podcast stands for having meaningful conversations with people who are thinking about health, about life about mindset in a way that we may not be getting on social media or in mainstream media. And so I just want to say give you guys a shout out and just say thank you for participating in this process with me, because as much as I absolutely love delivering the information to you, I love even more knowing that it’s impacting your life. So please let us know if there’s anything we can do to make this podcast more customized to you to make it better. We are now officially in season two. And we are working to bring you the best conversations that health influencers have that mindset changers can give and to really deliver you something that you’re not able to get anywhere else. So from the bottom of my heart, as I always say my YouTube from the bottom of my heart. I am deeply appreciative of you. I am deeply grateful to be on this journey with you and let’s get healthy together.