“Collapse of the microbiome equals human disease”
This episode is all about the epicentre of chronic disease and your microbiome.
My guest, Zach Bush, MD, of Farmer’s Footprint, has triple board certified expertise in Internal Medicine, Endocrinology and Metabolism, and Hospice/Palliative care. The breakthrough science that Dr. Bush and his colleagues have delivered offer profound new insights into human health and longevity. His education efforts aim to bring about radical change in the mega industries of big farming, big pharma, and Western Medicine at large.
In this podcast, The Epicentre of Chronic Disease and Your Microbiome, we cover:
- The Microbiome-Mood Connection
- Glyphosate Exposure and its Impact on Mood Disorders
- Healing Chronic Disease by Restoring our Microbial Intelligence
- Restoring Health and Regenerating Agriculture
The Microbiome-Mood Connection
In this episode, Zach joins me to shed light on the profound impact of the microbiome on our mood and mental well-being. In today’s world, we’re witnessing a staggering increase in mood disorders such as depression and anxiety, affecting not only adults but also our children and women going through menopause. Zach brings to our attention that over the past century, major depression affects one in two individuals, compared to just one in a hundred back in the early 1900s. This could be likely explained that this was tied to the chemical industry revolutionizing farming in the 1970s, introducing compounds like glyphosate, commonly known as Roundup – a potent antimicrobial agent, that disrupts the microbiome at multiple levels. We are exposed to it through the air we breathe, the food we eat, and the water we drink. Even those who prioritize organic eating and healthy lifestyles still have detectable levels of glyphosate in their urine. So, while choosing organic foods can reduce glyphosate levels, it doesn’t eliminate the problem entirely. Zach mentions by advocating for regenerative organic practices, we can not only improve our own health but also bring about positive change in the industry responsible for the widespread use of harmful chemicals.
Glyphosate Exposure and its Impact on Mood Disorders
The destruction of our microbiomes caused by glyphosate in the farming and consumer industries is deeply concerning, but we can take action with our health to decrease these levels. Glyphosate was initially used by homeowners, leading to its presence in water systems, Zach explains. Children, in particular, are highly exposed to glyphosate while playing in fields and parks where it’s been sprayed. This exposure is crucial because our brain and gut are interconnected through the gut-brain axis. Stress in the gut directly affects our brain, and vice versa. Recent research has shown a direct connection between the microbiome and the brain, with enteric endocrine cells in the gut producing neurotransmitters like serotonin and dopamine. Antibiotic use disrupts the microbiome and can lead to mood disorders, such as depression and anxiety. Antibiotic prescriptions in the US alone are alarmingly high, with 833 prescriptions per 1000 individuals.
Healing Chronic Disease by Restoring our Microbial Intelligence
The collapse of the microbiome, the loss of the gut barrier, and an overwhelmed immune system are the core factors contributing to chronic diseases. However, these effects extend beyond the gut. Glyphosate also affects the blood-brain barrier, kidney tubules, and the vascular system, as they share the same tight junctions. Consequently, leaky brain and leaky kidneys can occur, further impacting overall health. It’s important to restore our microbial intelligence to reverse these effects. Rather than relying on probiotics, which create a monoculture in the gut, a more effective approach involves reintroducing carbon resources that promote the diversity of the microbiome Zach explains.
Restoring Health and Regenerating Agriculture
Zach mentions the need to change the farming industry, as the current practices are causing chronic diseases in children and endangering farmland. Regenerative farming offers economic resilience, multiple revenue streams, and the potential to reverse our CO2 footprint. Contrary to popular belief, organic farming practices often affect soil health. By supporting regenerative agriculture, we can eliminate the need for farmers to rely on risky bank loans and welfare programs. Zach explains to achieve the dream of regenerative agriculture and a healthier future, consumer support, education, and active involvement are crucial. By healing the soil and promoting regenerative practices, we can create a sustainable food system and empower future generations to solve the pressing problems of our time.
Dr. Mindy
So let me just start off by saying welcome. So grateful wouldn’t be here.
Zach
So grateful to be with you all, it’s always exciting to connect the new community. So thanks for creating that opportunity.
Dr. Mindy
So welcome. Let’s start with this, what a big reason why I wanted to bring you on to resetter. TV and I wanted to expose my community, to your knowledge is that we are living in a time where we have so many mood disorders, we have depression and anxiety. And, you know, I’ve got a lot of women going through menopause, and we’ve got teenage anxiety. And there is such a strong microbiome connection that I really would love for you just to speak on that and help us understand how the microbiome really ties in to our thinking and our moods.
Zach
Fantastic. Before we dive into the kind of the molecular mechanisms by which this is kind of interrelated, and the intricate, co creative environment of the microbiome in your brain, I want to prove that this is true at the population scale, because it can sometimes get down into the weeds. And you may as an audience member feel like at some interesting theoretical data, or that’s some interesting scientific data than a microscope. But how does that really apply to me or my family. And what we can do is backup to a national kind of viewpoint at the United States and say, dial back to the year 1900 9010 kind of timeframe. Freud and his colleagues at that time out of Europe in the US collaborated on really what was at the forefront of evidence based medicine. Before we even had that terminology, they did some of the first really aggressive fantastically done statistical analysis on population, how. And so they did it on mood disorders, looking at major depression, anxiety disorder, psychosis. We didn’t use the word schizophrenia at the time, but they had different terminology for it. But these conditions got tracked very carefully in the population. And then that beginning of the last century, 100 years ago, we saw a prevalence of major depression and an anxiety disorders at about one in 100 individuals. Fast forward to the day, and we’ve hit one in two individuals major depression, incidents of over their lifetime, and then 113 for anxiety disorders. So extreme acceleration over the last century. And so if we just can now say, for sure, the population has an explosion of mood disorder, when did that really start to accelerate, and it looks like it really started in the late 1960s. And revved up through, you know, slow integral increases in the following decades. And that in the 1990s, things started to go vertical. And so that we call this a parabolic curve, or asymptote, where you start to approach kind of vertical incidence of a disease process. And that’s where we go into a true epidemic. And so you can have a rise in incidence. But when you go into that vertical rise, that’s when we can identify an epidemic. And over that same period of time 1990s to today, that short, 25 year period, we can say that with confidence, we’ve got cancer, heart disease, autoimmune disease, chronic fatigue syndromes, chronic pain syndromes, mood disorders, all the way down through childhood brain development, and geriatric degenerative neuro conditions like our Alzheimer’s and Parkinson’s, in the children, its autism and attention, deficit disorders, have all exploded at the same rate, very near the same rate, they’ve all gone epidemic into those vertical curves. And so that’s fascinating, and really points to an important truth, which is there was one event that happened in the 1990s that predispose the entire population in all of our genetic variability, all of our genetic variants and vulnerabilities. We all got sick in the same 20 year period. And amazingly, this is hitting the younger generations the fastest. And so the children who should be the most resilient are seeing the highest disease rates we’ve ever see. We’re currently tracking somewhere around 46% of children in the United States and other Western countries with a chronic disorder or disease by the time they’re at 46%, one in two children. And that’s in contrast to if you looked at the entire population in the 1960s. And as Western developed worlds, we had a chronic disease burden of about 4%. So we’ve gone from 4% of the entire population and 46% of our children with chronic disorder disease. That astounding statistic is really underlying, and really pointing to the truth that you’ve pointed to, which is there has to be one really important thing at the foundation of all of this mood disorder that you’re asking about. And so we’re going to now zero in on a couple of topics within mood disorder which might be anxiety In depression and children, young teens, as well as the high prevalence of these disorders and pre menopausal, Peri menopausal postmenopausal phases of life. And so just as we’ve done with cancer, heart disease, autoimmune disease, I can show you that there’s a marriage of the pathophysiology of these mood disorders in children versus adults at very different stages of their endocrine function. There are systems of biology in the rest. And so public data, the public health record really proves that we did something in the 1990s to undermine health period. And in that those categories, we have these mood disorders.
Dr. Mindy
Yeah. Which as glim, as that sounds, it also where my brain goes is, okay, so if we created this, we can uncreate this, we can change this. And maybe it’s like just changing a few things that will change so many conditions.
Zach
Precisely. And, you know, we’ve got this nutrition movement afoot right now called the Paleo diet and all this and they’re saying, Well, if we all ate his caveman, we would probably be healthier. And the reality is, if we just all ate as we did in 1965, we’d all be healthy, right? We don’t have to go back to some distant past to remember when people will become healthy on the foods that they ate. Even, you know, when I was in undergrad, you know, late 80s and early 90s. We feared that the approach of the Corn Belt football players, the Nebraska football players coming to Colorado would work as good. So often, we would kind of regard these farm boys as like the some other species like the optimal health. And tragically, if you go on to these farms, today, they are some of the sickest populations, you can find arm children. So they are really at the epicenter of what happened in the 1980s and 90s, which is we chemicalized, we created the chemical industry that we now call farming. And so we took farming out of 1000s and 1000s of years of practices that were in line with natural cycles of Earth regeneration, the natural cycles of soil, water and air. And we removed those qualities, or we gave up on those qualities. And we turned it into a warfare mentality where we started applying literal chemical warfare agents used to use a compound called Agent Orange to destroy the jungles of Vietnam and Cambodia in the late 50s. And throughout the whole 60s and early 70s. And so we decimated those jungles into Moonscapes. With the chemicals, the organophosphate family, I was agent. That same company, Monsanto would then exit the war strategy and move towards the farming industry in the 1970s as the war wrapped up, and they created another Oregon of organophosphate, just like Agent Orange, that would become known as roundup or the active ingredient glyphosate. And as we watched the march of that chemical industry, we see the undermining of farm health, ultimately food health and ultimately population health. And so my laboratory here in Virginia, I left the academic environment in 2010, University of Virginia and for that university Colorado, and and started my own basic science laboratories and biotech, working in soil and microbial intelligence. And out of that experience we’ve come on to be able to show unexpectedly, that Roundup is really the epicenter of the chronic disease epidemics that we see today. And so that roundup molecule turns out to not be ever patented as a weed killer by Monsanto or any of the other companies. Instead, it’s been patented as an antibiotic and its antimicrobial effect. It’s also been patented as an anti parasite, anti fungal and that like it kills the microbiome at multiple levels. Interestingly, in their own patents, Monsanto has revealed how this chemical works. And the chemical works by disrupting an enzyme pathway in bacteria, fungi and plants that create the essential amino acids. essential amino acids are the necessary building blocks for all protein. All proteins are the building blocks and the workhorses like enzymes of cellular structures throughout the entire multicellular world. And so whether you’re an earthworm or a human, you rely on a very small subset of these amino acids. Nine of the total category of amino acids are what we call the essential amino acids. Because we as multicellular organisms, like worms and humans can’t make these amino acids, the majority we can’t, but the nine essentials we are much like the vowels. These are the letters within the alphabet, that if deleted, start to affect every single word or every single protein that would come out of the the construction of those amino acids into their various sequences. And so in the 1980s and 90s, as we started to infiltrate our food system with this chemical, we started to delete the capacity of the soil microbes and the plants that would grow in them to build the the storage or database of essential amino acids. And so the whole planet has begun to misspell proteins, misspell proteins, we diminish function, whether you’re bacteria or plant, we can kill you very quickly because these are integral, you know faculties within you. And so we act as a potent antibiotic broad spectrum or broad spectrum and the the antibiotics we give a human typically. And so the most potent antibiotic them the earth right now is is is this roundup chemical. And unfortunately, it’s integrated into the food and water systems. Now, we are currently dumping about 5 billion pounds of this chemical into the world’s soils. And unfortunately, it’s water soluble, which means it gets into the runoff, it gets into the river systems in the oceans where it evaporates and ends up in our air and in our rain. 75% of the air we breathe in the United States can be measured positive for glyphosate, it’s 75% of the rainfall, glyphosate. And so we are breathing it, we’re eating it, we’re drinking it, it’s raining on us, it’s raining on our crops. So I really encourage everybody to go towards a organic and ultimately as we get the labeling right in our country, regenerative organic foods for the purpose, not just because it’s better for your health, because it will change the industry that’s dumping the chemicals into the system with the obvious reality that if you’re eating organic, you’re still eating Roundup, you’re still breathing Roundup is still right. That’s
Dr. Mindy
my question is to eat. So eating organic isn’t the total solution. If it’s ubiquitous, ubiquitous in our environment,
Zach
it doesn’t fix your your glyphosate toxicity problem, it reduces the level of glyphosate remarkably, but it doesn’t get you to zero. For example, we just finished a double blind placebo controlled study for restore our dietary supplement line. And in that study, we were tracking roundup levels in the urine of patients. And it’s interesting that here’s, you know, a group of consumers that are actually already on the health instead of the spectrum of consumers, they’re already aware of this organic stuff. They’re a lot of my followers and stuff like that. And so, you you, you distill down the healthiest population, and still we could not find a single person that didn’t have roundup in their urine. Yeah, that’s crazy. All eating, drinking and peeing out the roundup from our environment, which means it’s touching every cell membrane throughout your body. Yeah.
Dr. Mindy
So let’s so I’m putting this down to like the concept of I’m sitting there with either a team that has anxiety, or I’ve got some extreme mood disorders, what I heard and what you just said, is, hands down, the first thing you need to do is avoid your glyphosate exposure as much as you can, which would be going organic. Second step would be taking a supplement like restore, which I told you before, like I think I feel like I should walk around with a restore bottle. And like, I’m like your biggest poster child, because it’s miraculous. So can you talk about like, what that second step would be and how it would impact mood disorders?
Zach
Yeah, maybe before I get to the solution, I need to finish painting the relationship with that microbiome to your brain. Yeah. So the microbiome that we’re destroying through our farming industry, and frankly, also remember your consumer industry. And so, up until 1992, the main contributor to your water system of this chemical was was homeowners that were spraying roundup onto their driveways to kill the six or seven dandelions. And homeowners are not at all concerned about spraying, you know, $20 of a weed killer on a small driveway. Whereas farmers have to be very judicious with this because it’s their one of their main costs or inputs. And so they’re going to pay far less concentration than the homeowner does. So I’m pretty convinced that homeowners started poisoning each other by the late 80s, because we were spraying into our driveways and sidewalks, roadway systems, our parks and rec systems, our soccer fields. All of our children have been on school fields and soccer fields for 25 years now that have been being sprayed with this chemical. And and so now we say well, why do children have 46% chronic disease? Well, they’re literally running around eating it, rolling it out wrestling and, you know, breathing it, when they play soccer, or they play rugby, or they play football, or they go walk the dog in the park or they run around on the playground. They’re absorbing it through their skin. They’ve got you know, breathing, it’s like, literally steeping our children in this chemical. And so why does that matter to the brain? This exquisite research has been coming out of universities like UCLA use UCSF, and what they’re showing is that the human brain extends down through peripheral nerves into your gut. And for a long time we’ve we’ve now for the last 10 or 15 years, we’ve developed this whole science around what we now call the gut brain axis. And we’re now recognizing that any stress that happens to God immediately translates into stress in the brain. And vice versa. When the brain stressed out it screws up gut function. And so we’ve we’ve demonstrated There’s two way communication between the gut and the brains. We call that the gut brain axis. We have a belief that things outside of the world like the bacteria and the fungi that thrive in our guts and in our skin, and in every orifice of our body was somehow, you know, passing information through into the system that would eventually get to your brain. What UCLA and UCSF have recently done is start to show this exquisite direct connection between the microbiome that is in and around your body and your brain. There’s a series of cells that are called the enteric endocrine cells, they represent 10 to 15%, of all of the cells that make up your gut lining. Remember, your gut is not your stomach, your gut starts at your sinuses includes the entire upper GI tract, I would include the respiratory tract there too, but that’s probably controversial, but at least the upper GI system, the stomach, the small intestine, and its huge entirety, and the massive cold. And so from nose to rectum, you are this one kind of digestion track, if you will, where you are microbially dominant, you are probably 100 to one represented, if not 10,000, to one representative in the microbiome to the human cell environment. So you have this giant tube system, and the tube is protected from your body by a single cell layer. And that single cell layer is half the width of a human hair. And so picture a layer of cellophane, that’s half the thickness of a human hair. And that covers two tennis courts and surface area. That’s your that’s your gastrointestinal membrane, or barrier system. Now you put on top of that, all your food and the chemicals you ingest, and everything else. And you have to absorb what you would like to absorb and keep out what you would like to keep out. So that barrier system is an intelligent membrane that will try to be that selective barrier to keep the good sides in or bring the good stuff in and keep the bad stuff out. About 10 to 15% of those cells are not just barriers, they’re actually the the manufacturer for your neurotransmitters. And so these are the enteric endocrine cells. And so 10 to 15% of that giant cellophane layer produced 90% of the serotonin that gets produced in your body, and over 50% of the dopamine produced in your body. At that point, you can say, well, at least the brain makes 50% of its dopamine. And of course we’re wrong again. 40% of your body’s dopamine gets made by your kidney tubules. And so between your kidneys and your gut make 90% of your dopamine, your gut alone makes 80% of your serotonin. So you start to realize these two major transmitters that have been blamed for your anxiety and depression actually are not at all related to your brains, disease or disorder process. If you have depression or anxiety, you have a deficiency of workhorses in the gut. Well, how did that happen? Here’s where the the data out of these universities gets kind of trippy. As in recent three dimensional imaging at the molecular level, we’ve been able to show that the human neurons are extending past that cellophane layer and actually listening directly to the bacteria and fungi in your gut. Wow, bypasses your barrier system, so that your brain can talk directly to bacteria. Simultaneous to that anatomical discovery, it was being discovered since 2014, that if you remove certain bacteria from the gut, those enteric endocrine cells can no longer make serotonin and dope. And so your you cannot produce the neurotransmitters and your brain cannot listen directly to the full gamut or the full ecology of a healthy ecosystem. When you take an antibiotic, you decimate that microbiome amazing studies coming out recently show that one course of antibiotic for an upper respiratory infection or something like a urinary tract infection, you grab that antibiotic for your dog, your chance of a major depressive episode goes up by 24% in the next 12 months, and the chance of a generalized anxiety disorder developing goes up by 17%. In one round one box. If you now go back to your doctor within that 12 month period to get a second round of antibiotics, you had your UTI treated six months ago and now you go in for your bronchitis or sinusitis. That second course of antibiotics now raises your risk of major depression by 54%. And your risk of anxiety disorder by 44%. And so we are having massive decimating effects on mood disorder through our antibiotic prescription behavior as physicians because all these is the same process. It’s ultimately dysregulation of communication and chronic inflammation. Cancer has the same pattern. And so if you look at the maps that I show, in all my lectures I’ve I’ve I’ve put side by side the CDC maps of cancer death with the New England Journal medicine articles that have showing that antibiotic prescription havior per state, and you can see a perfect state by state correlation with the more antibiotics prescribed per population. The more cancer death we have out. And so in those two demonstrations I’ve been able to show at the population level, antibiotic usage from your phone from your physician and pharmacy drives mood disorder and cancer death, crazy claps with the microbiome equals human disease. Now let’s back up and ask how much antibiotic is being prescribed by our physicians. Were somewhere around in the United States, a disgusting 7 billion pounds of antibiotic per year prescribed crazy descriptions, but pounds, what that equals out to is 833 prescriptions of antibiotics for every 1000 men, women and children. And so we’re somewhere around 83% by the numbers of the population, and there’s probably some redundancy, it might be more closer to 40% of the population where a lot of the population is getting two quarters of an inbox in here. But suffice to say 133 prescriptions for every 1000 Man, woman child, that’s a lot of antibiotics. That’s the 7 million pounds. But in the United States, we use around 300 million pounds of of Roundup. And so yeah, we are many longer that was greater in our antibiotic exposure through our farming industry and agriculture, and our landscaping and streets, you know, Parks and Rec services and the rest, then we are at risk from our doctors. And so the real collapse of health is happening from roundup spraying. We’ve proved this by looking at the the concentrations of Roundup spray, and the water systems in which that roundup ends up. The largest of these is the Mississippi River. The missed the tributaries of the Mississippi River cover about 80% of the country. And or I’m sorry, 80% of the roundup spreading in the country, a footprint of maybe 60% of the country. And so with 80% of the roundup that we spray in the whole country being absorbed into a single water system, it’s going to be concentrated ultimately in the last 90 miles of the Mississippi River, which runs from Baton Rouge to New Orleans, Louisiana. And that happens to be called cancer alley. That’s the highest rates of cancer in the entire developed world by an extreme amount. Interestingly, that deep south was never the epicenter of cancer death in our country, up until 2007 hit. And so 1997 and before our cancer death maps were northeast and northwest, and that suddenly in the 13 years between 1997 and 2004. We cause this decimating injury to the microbiome to the Midwest that concentrated the chemical that would wipe out the microbiome of the Deep South. And we would create the highest rates of cancer in the world. And of course, mood disorders right there. In Italy, this is work now by
Zach
norm Shealy, who is running the largest pain clinic in the United States for over 30 years up in Wisconsin area. And his pain clinic realized early on in the late 70s, early 80s, that an enormous amount of the patients that were presenting with pain, had predisposing mood disorder. And so he ultimately became the biggest Center for Integrative medicine approaches to treating mood disorder, because he figured out that mood disorder happens shortly before chronic pain syndromes emerge. So a major depression in the recurrent state will then turn into a chronic pain syndrome, if not treated at its core. And and so we can say in the population, if you have major depression, anxiety disorders, everything else, and that becomes a recurrent theme where you’re now at your second or third bout of major depression, the chance of you divide developing fibromyalgia, regional pain syndromes, like Reflex Sympathetic Dystrophy, or chronic regional pain syndrome disorders, those guys are all could have been captured earlier and prevented if we had recognized the relationship between the claps and their microbiome, the emergence of mood disorder and their march towards that chronic pain syndrome, and ultimately, to the cancer that would follow.
Dr. Mindy
Yeah, you know, I’m watching the comments that are coming in, and everybody’s like, Oh, my God, mind blowing this is, you know, it’s such a message that, that we need to get out. And I have to tell you, Dr. Zack, the first time I heard you speak, I actually cried. I just I just had wept, because everything you say, makes perfect and logical sense. And yet we’re all living in this world together. So how do we how do we emerge from that? And what do you know, the connection is so clear, and how do we overcome this?
Zach
Yeah, I’m gonna, you know, for full transparency because whenever you hear my talk, or anybody hears my talk, there’s a major risk that you’re gonna think I’m intelligent. I want you to know that I asked back my way into all of this information. Yeah, it was total mistake that I got from the place that I am today. 10 years ago, I was developing chemotherapy at the University of Virginia. So I went from extreme pharmaceutical mindedness and now where I am today, and my current mindset around nature is our healer and that’s our disconnect from what’s causing this chronic disease epidemic. But to kind of catch you up on how I got to the realization of the roundup through some brilliant people, I work with Dr. Dr. John Gill day number one among them. But he was the one to really figure out this roundup link to the soil, and what we’re seeing at the molecular level human cells. But when I had brought to Dr. Gill de, was actually the solution to this injury. And I didn’t know about this injury, I didn’t know it was gonna be a solution to it, I was still in my cancer mindset. But I had found some molecules in soil, namely, and actually ancient fossil soil that were doing some pretty phenomenal things in my clinic. And they were very similar to the molecules I had used in the chemotherapy world, but there was no toxicity to them. And so I had him start studying them under the microscope. And we proved out extraordinary safety levels, these molecules. And then in the end, when when I started putting these into my cancer patients to improve their nutritional recovery after after chemo, and everything they’ve been through, we started to see things that I didn’t expect, I had seen, they expected to see things in the cancer world, I had no idea what I was going to see shifts and autoimmune conditions, chronic inflammatory states, you know, 40 year decades worth of a GI distress and problems were reversing. And so all this stuff was was going into some sort of repair process I didn’t understand at all. And so it was bringing all that back to Dr. Delays attention. And in his PhD mindset, he you know, quickly started putting the pieces together to say what could we be doing at the population level that could be reversing so many chronic disease situations. And so he was the one that tie this all back to the leaky gut phenomenon. And leaky gut is actually at its core, what happens when you ingest Roundup, and so it has the antimicrobial properties of kills bacteria, fungi, both in the soil and your gut to leave you depleted of your your bike microbial workforce. But then it does further direct damage to the human biology by destroying the velcro and the tight junctions that bond all those billions of cells into that two tennis courts of surface area. And so as that that cellophane turns into a sieve, you start absorbing everything from your environment inappropriately. And what it results is a massive amount of inflammatory response. Now you’re reacting with pollen you breathe, to the dust you breathe, to the water, you drink to the dairy you consume, the food you eat, the kale that you eat, all these foods start becoming inflammatory to your body and you start to develop severe irritable bowel syndrome, esophageal reflux alterations, chronic inflammatory bowel disease, Crohn’s disease, ulcerative colitis, autoimmune conditions, thyroid, rheumatoid arthritis just now that now just all start spooling out from an overly inflamed, overly activated gut that’s no longer protected from the outside world. Though, as we look at these three pieces, you’ve got the collapse of the microbiome, the sudden leak and loss of barrier to the outside world is your your tight junctions fall apart, and then your immune system overwhelmed happens. That’s the three pieces that are fundamentally at ground zero. If we then watch the trickle down effects back to mood disorder, it turns out that the blood brain barrier and the kidney tubules and the whole vascular tree are tied together by the same tight junctions. And so it turns out that glyphosate hits your gut and creates leaky gut within minutes. You have leaky brain, and leaky kidneys.
Dr. Mindy
I haven’t heard leaky chimney. I’ve never heard that, but makes perfect sense. It’s,
Zach
it’s all the same protein structure and all vulnerable to that roundup injury. And so we’ve been working to show that the the microbial intelligence that we’re pulling out of the soil can actually reverse all of that. And so first of all, we create a boom in the microbiota when we put these, these carbon resources back into a biologic system. So we can diversify, rather than simplify that which the probiotic industry does. Probiotics create a monoculture in your gut, you don’t want three species of bacteria, you want 30,000 species of bacteria. And so we don’t have a probiotic that actually works to diversify your flora. At best. There’s there’s little tiny band aids that you can throw on momentarily. You stay on a probiotic, it’s actually been recently shown and published and cell that actually narrows the microbiome just as badly as the antibiotics do. So why history needs to disappear as soon as possible. In contrast to that, if we give no microbial micromanagement instead, just get back the communication network that coordinates behavior between the species, then we get balanced and diversification happening. And so again, this is soil intelligence coming back into play in biology. When we add that to human cells, they immediately start making protein enzymes that are responsible for detox doing genomic repair. It’s just an incredible event. And interesting these molecules don’t do anything on they’re out. The supplements that we now derived from them are the only supplements in the market that tried to do absolutely nothing. They are trying to be completely House of players in biology to give back the wireless network that you would correlate very much. So with your cell phones, your cell in their body is very much like a cell phone has all of the machinery inside of it to transmit and receive information from the greater organism. But if you lose the wireless communication network from the microbiome, that we now know, is transmitting information between cells, you now become an isolated cell phone, within seven miles away from the closest cell phone tower, you suddenly can’t connect, and the whole cell starts to stagnate, your software can’t update, you can’t communicate with any other humans on the planet, you start to become an isolated and lonely entity. What you have just become at the biomedical standpoint is a cancer. So a cancer cell only becomes cancer when it comes totally isolated from its environment. And so first, to do that, you have to cut all the tight junctions, which is what roundup does. The World Health Organization is now finally identified as a probable carcinogen, you need to delete the word probable out of there it is a carcinogen. But we have a carcinogen that’s creating what lonely cells and simultaneously killing the microbiome that would produce the communication network, or the wireless communication that would help one cell speech to the other. And so in in really one chemical, we’ve got the perfect isolating chemical that we’ve created. And hasn’t that been what we’ve seen at the macro level, human, 7 billion on the planet, never more of us here are more isolated than we’ve ever been, despite the internet, Facebook, Twitter, all these connected devices, I would argue we’ve never seen a higher level of loneliness, isolation, suicide, et cetera, in our civilization, and so really fascinating that at the microbial level, and at the human cell level, we get isolation, loneliness, and the result is immediately at the macro level isolation, loneliness egocentrism, we forget we’re part of a larger human organism called homosapien, we lose the identity of species. We choose nationalistic, paranoia over globalist thinking, and all of the rest. And so we really see this outpouring of anger, hatred, fear mongering, everything else in our politics, paralleling the mood disorders that we see in the individual patient paralleling the biology of collapse of information stream at the cellular level.
Dr. Mindy
Yeah. And it makes perfect sense because we’re physiologically disconnected and within ourselves, that would totally make sense that that would play out in our outer world. So so how do we how do we fix this? Like, I think any solution always starts with awareness. And then we got to wake people up. And now what do we do?
Zach
Fantastic. Yeah. So since early on the biotech side, companies are doing very well, we’ve developed the human line of supplements. Restore is the name of the supplement that you mentioned. But we’ve also developed incredible supplements for the feet in the food industry. And so we go in our initial sales to the large ag system in gin, at the Global vet Health Group, which spent last four years getting approved as a low risk drug in Canada, it turns out, you have to be regulated as a drug to go into the human food chain. And so we’ve gone through all the science rigor and everything else necessary to get there. And so we get our nn number at the end of this month, and we will be getting this product into your food chain, which is going to immediately reduce the stress of those animals in the feedlots, etc. And I hope it’s a stepping stone to real humanitarian management of our protein production systems of poultry, swine, and the and the beef industries that are just horrifically catastrophically painfully mean to these animals. So we’ve we’ve got to get a higher ethic in this industry. And we hope that this is the science and the industry of communication, the cell level was our slippery slope into a higher ethos of animal care as we go. And so these products are going to hit the market and the human was already gone global. We’re in over 120 countries in the United States were sold in over 900. physician offices, it’s kind of frontline management for for health, and disease prevention.
Dr. Mindy
And that and so just so everybody knows that you’re referencing restore, is what you’re referencing. Yeah, and I cannot say enough about the what a game changer Restore is for a functional medicine doctor like me, like, I it is a game changer. And people ask me all the time, like, how long should you be on? You know, how long do I need to be on it? Some people say I don’t really notice anything on it. And I just say, keep taking it, taking it.
Zach
Yeah, there’s a couple of great points. Number one, you know, how long do I take it until we change the industry? And so and so we stopped spraying these chemicals and under our environment, we’re going to be reliant on these on these compounds from the soil. I think it’s pretty fascinating that the only place that we find these carbon molecules and insufficient diversity is in soil that’s about 60 million years old or older. That’s pretty fascinating because what we’ve shown is that it functions as the antidote, if you will, to round up, because if you put it on a cell membrane that’s been damaged by Roundup, within six minutes, you see regeneration of the proteins that have been damaged. And you see that leaky cells start to zipper back together in just minutes. And then within six to eight hours, you haven’t, you’ve surpassed the original integrity of that membrane. Within six days, we’re measuring levels of resistance across those membranes that have never been recognized as possible. We’re the first laboratory in the world to be able to create high trans epithelial resistance in kidney tubules. And so from gut all the way to kidneys, and we’ve proved down on blood brain barrier as well. So got blood brain barrier, and kidney tumors all come back online, creating these resistant barrier systems of intelligent barriers, by reconnection to this wireless network. And let me remind you that restore does nothing, it doesn’t actually prevent disease, it doesn’t treat disease, it doesn’t do anything intentionally. It’s actually inspiring. And this is the thing that gives me goosebumps more than anything else. All it’s doing is reconnecting you and all of your 70 trillion cells to your intrinsic capacity to heal. So you have all the intelligence and all the machinery to heal yourself from anything. It doesn’t matter if it’s cancer, heart disease, mood disorder, you name it, you have all the machinery to repair that into infinitum. The only time we see disease eMERGE is when there’s a failure of communication. I believe that’s true in our politics as well. The only time we see war is when we have a complete collapse of communication between humans. And so we need to learn from this and start to integrate information technology at the macro level of connecting humans. And then our company is working on that very actively to reinvent the internet, take it away from the big advertisers take big data manipulation and commoditization back into our own hands. And say, We the people on the data, we the people control our space. And we’re going to connect humans just as we would connect cells together with restore, and we’re going to restore civilization, not just human health. And so that’s my big dream. That’s my big passion right now, where I put a lot of my focus. But second, part of your question there around your second answer to your first part of the question there around how long do we take this is, I would like to invite all of you to as fast as possible for my biotech companies out of business, I do not, it is boring for me, frankly, to go in and fossil soil and turn it into the freakin supplements, and get that into your hands in a bottle that you go and drink. What inspires the hell out of me is imagining that your grandchildren, my grandchildren, will instead go into an environment where the first thing that they are taught as they enter preschool is how to grow a plant. The second thing they’re taught is how to get lots of plants growing and communication. And then by the time they’re in high school, they’re studying microbial quorum sensing and the intelligence of complex micro ecosystems and how they create intelligence and human beings to create a higher level of consciousness and behavior and their generation. That’s my dream. And so help me get there, we actually need to change first, the farming industry, we can’t have 46% of our children with a chronic disease. And unfortunately, one in 30 children with autism, our rate of autism is clitic. Climbing so fast now that we’re going to hit one in three children with autism in the United States, by 2035 16 years from now, one in three children with autism spectrum disorder, that population will not be able to be the creative, productive group that we need them to be. But when we support the health of those autistic children, we find them to be the biggest outside the box thinkers that have ever existed. I do believe there’s a silver lining on this autism syndrome, and that they will be the angels among us. If we create the space for them, and we put resources around them, give them health back there artistically wired minds will come up with solutions we’ve never dreamed of when we’re wired like we are. And so put my biotech companies out of business as soon as possible by healing the soil so that our children will heal and they can fix the bigger problems that will come down the pike now. And so how do we do that? Yeah, in fact that we launched farmers footprint, which is a nonprofit, we have launched a multinational approach to educating farmers who are currently stuck and frankly, they are trapped against their will in a in a economy that forces them to grow genetically modified crops. We’re teaching those chemical GMO farmers how to make the transition independently to their own economy and become independent again in food production. And to do that, we need your help. And so farmers footprint has become this extraordinary avenue through which consumers can suddenly be plugged back in directly to our food producers. These farmers are the most inspirational problem solvers you will ever meet. They do not want to be growing chemically filled foods for you. They want to grow real food, they want to actually kill their family soil, because they know that that’s all they have to pass on to their future generations. 8000 Farms a year are going out of business in the United States. 8000 farms have, you know, average sizes between 303,000 acres. And so we’re losing millions and millions of acres of farmland Every year now. And unfortunately, from a homeland security standpoint, we aren’t even selling that to Americans. Most of that is being bought up by international conglomerates, Russia, China and other countries owning our most prime farmland, because we can’t keep our farmers in business. The whole lie that’s coming out of the chemical farming industry say that we have to feed 7 billion people therefore we need GMO. Right? GMO crops don’t even feed humans, all of our crops. Look at Kansas as our biggest corn producer in the country. 90% of the land by square miles in Kansas grows GMO crops 90% of the food that’s consumed and Kansas is imported into the state, they don’t even grow their own food. The extraordinary thing is one in four children in Kansas goes to sleep hungry. We need to literally have starvation going on in the most agriculturally active environments of our nation. Not only are we not feeding the world with those GMO crops, we aren’t even feeding our own. It is an absolute humanitarian crisis going on on the ground right there. And we are finding that by just getting consumers to support through very mild amounts, we will be at $100 per acre $100 to sponsor an acre of dead chemically abused land, within one season, within 112 month period, we can get that land back to where it was before the 1980s. And so we can regenerate 30 to 40 years of ecosystem and everything else in a single full cycle of cover cropping and animal husbandry on that land. And so an incredible opportunity for us to co create with Mother Earth to reverse the toxicity, create truly regenerative land, which by the way, is capable of within the next 10 years reversing our entire co2 footprint that’s contributing to the global warming. Wow. And so we can solve global warming, starvation, food industry, the medical system at large through one practice, which is regenerative farming, much different than organic farming. By the end. By the way, most of the organic farms in this country have worse soil than the chemical farms. We are abusing the soil and our organic practices just as badly as we are in the chemical industry. And so our education system, and we have partners that have been doing this for decades, that are extraordinary experts in the industry, we’re just now scaling them by putting sewers back in and direct support to these farmers and educational systems. Our goal is to regenerate 5 million acres over the next six years, we need your help, you can actually produce 400 to $500 10x the economic return on that acreage by going regenerative, and your great economic resilience because instead of one or two economic streams coming out of selling your soybean or corn, you actually have six to eight revenue streams coming off that land that are actually year round. And so you eliminate the needs for this huge risk of the farmer to take these huge bank loans to get them through the year to pay off suddenly, when their harvest comes in. If their harvest fails, hail, etc. They fail completely. That’s when the US government steps in with the Farm Bill, which then pays out through what’s called the crop insurance, which is not an insurance program at all. It’s a welfare system for failing farms. Turns out the welfare system won’t pay you out unless you’re growing. The Farm Bill supported agricultural items of alfalfa, corn, soybean, all these genetically modified crops. Because the banks are not protected. Without the crop insurance, they won’t lend the farmers money to do regenerative agriculture. And so they have to grow corn and soybean to be able to borrow the money to grow craft that always in the earth and don’t ever end up on a dinner plate. Most of those Mises Where’s all that corn and soybean going, I forgot to tell you that it’s not going to dinner plates, most of it’s actually going to the fuel industry. It’s going into ethanol. And as fuel additives, it’s going into plastics production, it’s going into your clothing in the form of polyesters. And all the apparel industry, we don’t even grow food, we grow plastics, that’s where all that corn and soybean is ending up. A small percentage of that ends up is crappy feed for our dogs, cats and our animals at large. But there’s so much chemical residue in those corn soybeans at the time of harvest, that it’s very dangerous to put that into the food system of humans and so we keep kind of sequestered away. Chronic kidney disease is now the leading cause of cats that’s developed over the last 15 years as we’ve contaminated their food supply
Zach
the Hi, I’m sorry, my daughter’s like a super passionate dog person.
Zach
Current numbers of cancer in dogs right now is that for every 1.6, for dogs, less than one in two, there is a case of cancer now. And so we’re nearly at 100% of dogs now with cancer because of what we’ve done to their food. And so it’s, you can’t measure the humanitarian crisis on the human level. But then when you start to expand out to what’s happening to chickens, and the horror that they go through in that short lifespan that they have the horror of being a pig in a swine factory, or the war of being a loved animal that’s fed poisoned every day, unintentionally, by their owner, is just on every level wrong. And so my outcry to you this just help the farmer, the farmers are so good. They I’m sorry, this doesn’t usually happen to me.
Dr. Mindy
No, no. So appreciate your passion.
Zach
The farmers when they hear these lectures, it’s so emotional for them to imagine realizing that you’re poisoning the world, like it’s, that’s too much information to handle. It’s too intense, without the promise that we’re all in this together. And the recognition that we as consumers created this chemical industry, we outsource our food production in 1945. And World War Two, we were producing 40% of our food chain in our backyard gardens and called victory garden movement. Now we are growing less than 1/10 of 1% of our food, we have become so lazy, so disconnected from food production. And so in addition to helping the farmers and supporting them with not your not your just your money, they actually not interested in him as he’s the opposite, that they want to partner with the world. And so the hedge funds and all these other investment funds are working with us now to create investment strategies where you as consumers will ultimately be able to invest in your farmers, rather than just give to them. And so we’re going to go through a period of a pure nonprofit where you’re directly pour your love into these farmers and supporting them. But know that our organization is quickly working to create private sector solutions, investor based solutions that will empower you to become partners to these farmers, which is really what they want. They don’t they don’t want a handout. They want good business and they want to be part of good business. And they will solve our biggest problems. I guarantee you the physicians and scientists that are studied by molecular biology will not solve our health crises, they cannot because they are not at the root cause of the problem. Your farmers will solve the problem of global warming of the collapse of the ecosystems on the planet at large. Keep in mind that we are currently losing one species to extinction every 20 minutes. The rate at which we are collapsing biology on earth has never been witnessed, at least not under human hands. There has been five other great extinctions on the planet, only one of them hit 97% of collapse of biology on the earth. And we’re on track to be another one of those nights or 7% Death Events. Extraordinarily, if you look at the biological collapse of human function, even just at sperm levels in Western countries, our sperm levels have dropped by between 52 and 58%. In just 20 years. As we continue down this trajectory, we currently have about one in three males that are at risk of being infertile by low sperm counts. And as we go down another 20 years, we’ll have some 60s 30%, another 40 years, we hit some 85 90% of males in fertile. You extract that out to seven years from now and we hit human extinction. Through the pressures of chronic disease and the burdens rising there in coupled with our infertility rates, we will be extinct in seven years. Frankly, from my heartbreak over the animals and for planet Earth itself. I can’t wait for us to disappear unless we’re willing to transform. I do not want restore or any other substance to improve human health unless you’re willing to transform. If you’re in a net, continuing your current consumer behavior and accelerate the death of the planet, I don’t want you to have restore. I want restore to be a pivot point for you. I want it to be a realization moment that you are the neediest of change on this planet. And as a consumer you drive the boat to the farmers you drive the boat you drive the boat on all massive companies. two weekends ago I was in celebration mode mode with my company because after pounding this drum for years, we see 55% of the stockholders and bear revolt and give a vote of non confidence to their CEO for having bought Monsanto and do what they’re doing. And so we are shifting massive mega billion dollar corporations through consumer aware doughnuts. And so if you’re going to take restore, do me a favor and don’t be part of the problem become part of the solution for humanity which is going to be rising consciousness to realize that you need to make sure that everything you do in a day you take Mother Earth into consideration. You wonder about your footprint and your positive co creative regenerative capacity to work with her to make more life not less other
Dr. Mindy
amazing, amazing I’ve I’m speechless. Let’s let’s leave with this. So if you’re touched by this interview, please do one of two things share it out and donate and it gives us some action steps is it farmers footprint they go and donate and get involved and financially is there other ways to get involved other than financial?
Zach
Absolutely, farmers footprint.us is the the nonprofit website and coming within the next eight weeks, so you know, continue to fuel our efforts, we’re still we only have one paid employee. So all the money is pouring right into to all of this effort to get coordination all these levels but we haven’t townhall local activism packet coming out. That’s going to equip you as a consumer with PowerPoints, the the the print material and need the Docu series, we have the first 22 minute documentary film available to you. And so you can create a town hall event in your school, your community, your church, and take these resources. Amazingly, Kim from from Irvine, California, and her little nonprofit has made available her entire notebook on how to get roundup banned from your your entire county. And so all the steps you need to take and the science you need to give and importantly, the alternatives to roundup that your park systems and municipality, regulatory groups need to use instead of the roundup. And so it’s a solution based packet that gives you all the steps to get roundup banned from your county. It worked in Irvine, California, and just worked in the entire county, Miami, the largest county so far to round up as an entire county. So become part of that revolution. If we can get you know, 15% of counties in the United States to ban this chemical, we will collapse the whole industry of this chemical demand. So let’s make you guys notices of change. Your support is vital to our growth. But you ultimately are the real solution kind of force out there for the revolution to really happen.
Dr. Mindy
Yeah, and we can find all that on armors foot, that’s where everybody goes. So you know from the bottom of my heart like I just am so grateful for you. I’m just grateful for what you’re doing and how you show up in the world. And we will definitely the resetter tribe is is a mighty force and we will get this out to the world for you. So thank you for being here and thank you for doing what you do.
Zach
Thank you so much for having me on thank you all you give me hope. It’s the movement of the forces the movement of the troops that gives me a sense of there is still hope for our humanity to reintegrate into nature and a co creative process applied regenerate. So thank you for your your passion and your attention tuning into this
// RESOURCES MENTIONED IN THIS EPISODE
- PurityWoods
- Paleovalley
- Joovv
Loved, loved, loved this podcast’s topic. I have learned so much and would love to be part of the solution. I’m not financially able to donate at this time, but will as soon as I can. I’m scared for son and the future of all our children.. I really want to follow and be a part of this healing of humanity and the planet. It’s wonderful that their is a solution for all this.
Hi! Loved the episode I am interested in restore I have been on a roller coaster for 18 years I would love to try this product ! Where can I find a functional medicine doctor with the product in Las vegas
Can I get the website for the restore product. Loved the info on this podcast and I’m sharing it.
Here’s the link for Restore: bit.ly/40LV30q
Hey Mindy,
Zach mentions a lady in Irvine who got roundup banned in Irvine, CA. He says she offers a packet with info to present to local counties. I’m having trouble finding the packet online, any ideas?
Thank you.
What an interesting, eye opening, heart and gut wrenching podcast. Zach Bush is so passionate about the Microbiome and how we are destroying our planet and the people in it. We need to change and spread the word. Thank you for bringing this to light. We all need to make small steps towards a united goal before it’s too late.